19 research outputs found
On Hamilton cycle decompositions of complete multipartite graphs which are both cyclic and symmetric
- Author
- Publication venue
- Marshall Digital Scholar
- Publication date
- 01/01/2021
- Field of study
Get PDFLet G be a graph with v vertices. A Hamilton cycle of a graph is a collection of edges which create a cycle using every vertex. A Hamilton cycle decomposition is cyclic if the set of cycle is invariant under a full length permutation of the vertex set. We say a decomposition is symmetric if all the cycles are invariant under an appropriate power of the full length permutation. Such decompositions are known to exist for complete graphs and families of other graphs. In this work, we show the existence of cyclic n-symmetric Hamilton cycle decompositions of a family of graphs, the complete multipartite graph Km×n where the number of parts, m, is odd and the part size, n, is also odd. We classify the existence where m is prime and prove the existence in additional cases where m is a composite odd integer
The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbasi B.
- Abbasi-Kangevari M.
- Abbasi-Kangevari Z.
- Abbastabar H.
- Abd-Elsalam S.
- Abdelmasseh M.
- Abdoli A.
- Abebe H.
- Abedi A.
- Abidi H.
- Abolhassani H.
- Abu-Gharbieh E.
- Abubaker Ali H.
- Achappa B.
- Acuna J. M.
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Get PDFBackground: In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15–39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods: Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15–39 years to define adolescents and young adults. Findings: There were 1·19 million (95% UI 1·11–1·28) incident cancer cases and 396 000 (370 000–425 000) deaths due to cancer among people aged 15–39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59·6 [54·5–65·7] per 100 000 person-years) and high-middle SDI countries (53·2 [48·8–57·9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14·2 [12·9–15·6] per 100 000 person-years) and middle SDI (13·6 [12·6–14·8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23·5 million (21·9–25·2) DALYs to the global burden of disease, of which 2·7% (1·9–3·6) came from YLDs and 97·3% (96·4–98·1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation: Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Funding: Bill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, St Baldrick's Foundation, and the National Cancer Institute
The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali A
- Ab Khan M
- Abbas Q
- Abbasi B
- Abbasi-Kangevari M
- Abbasi-Kangevari Z
- Abbastabar H
- Abd-Elsalam S
- Abdelmasseh M
- Abdelwahab AA
- Abdoli G
- Abdulkader RS
- Abdulkadir HA
- AbdulmuhsinMohammad K
- Abedi A
- Abegaz KH
- Abidi H
- Aboagye RG
- Abolhassani H
- Absalan A
- Abtew YD
- Abu-Gharbieh E
- Achappa B
- Acheson AR
- Acuna JM
- Addison D
- Addo IY
- Adegboye OA
- Adesina MA
- Adnan M
- Adnani QES
- Advani SM
- Afrin S
- Afzal MS
- Aggarwal M
- Ahinkorah BO
- Ahmad AR
- Ahmad R
- Ahmad S
- Ahmadi S
- Ahmed H
- Ahmed LA
- Ahmed MB
- Aiman W
- Ajami M
- Akalu GT
- Akbarzadeh-Khiavi M
- Aklilu A
- Akonde M
- Akunna CJ
- Al Hamad H
- Al Montasir A
- Al-Hanawi MK
- Al-Maweri SAA
- Al-Raddadi RM
- Al-Rifai RHH
- Al-Sabah SK
- Al-Tammemi AB
- Alahdab F
- Alanezi FM
- Alanzi TM
- Alessy SA
- Algammal AM
- Alhassan RK
- Ali AH
- Ali BA
- Ali HA
- Ali L
- Ali SS
- Alimohamadi Y
- Alipour V
- Aljunid SM
- Alkhayyat M
- Almustanyir S
- Alonso N
- Alqalyoobi S
- Altawalah H
- Alvis-Guzman N
- Amare F
- Ameyaw EK
- Amirzade-Iranaq MH
- Amu H
- Amusa GA
- Ancuceanu R
- Anderson JA
- Animut YA
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- Traini E
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- Ullah I
- Ullah S
- Unnikrishnan B
- Vacante M
- Vaezi M
- Valdez PR
- Vardavas C
- Varniab ZS
- Varthya SB
- Vaziri S
- Velazquez DZ
- Veroux M
- Villeneuve PJ
- Violante FS
- Vladimirov SK
- Vlassov V
- Vo B
- Vos T
- Vu LG
- Wadood AW
- Waheed Y
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- Wamai RG
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- Wickramasinghe ND
- Woldemariam M
- Woldu B
- Xiao H
- Xu R
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- Xu X
- Yadav L
- Yang L
- Yazdanpanah F
- Yeshaw Y
- Yismaw Y
- Yonemoto N
- Younis MZ
- Yousefi Z
- Yousefian F
- Yu C
- Yu Y
- Yunusa I
- Zahir M
- Zaki N
- Zaman BA
- Zangiabadian M
- Zare F
- Zare I
- Zareshahrabadi Z
- Zarrintan A
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- Zeineddine MA
- Zhang D
- Zhang J
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- Zhang Z-J
- Zhou L
- Zodpey S
- Zoladl M
- Publication venue
- Publication date
- 20/08/2022
- Field of study
Get PDFMapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
- Author
- Abbasalizad-Farhangi Mahdieh
- Abbasi Masoumeh
- Abbastabar Hedayat
- Abdelalim Ahmed
- Abdoli Amir
- Abdollahi Mohammad
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Nebiyu Dereje
- Abebo Teshome Abuka
- Abegaz Kedir Hussein
- Abolhassani Hassan
- Abreu Lucas Guimarães
- Abrigo Michael R. M.
- Abushouk Abdelrahman I.
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Adabi Maryam
- Adebiyi Akindele Olupelumi
- Adedeji Isaac Akinkunmi
- Adekanmbi Victor
- Adema Bereket Duko
- Adeoye Abiodun Moshood
- Adetokunboh Olatunji O.
- Adham Davoud
- Aduroja Posi Emmanuel
- Advani Shailesh M.
- Afarideh Mohsen
- Afshin Ashkan
- Aghaali Mohammad
- Agrawal Anurag
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadi Sepideh
- Ahmed Muktar Beshir
- Ahmed Rushdia
- Ajumobi Olufemi
- Akal Chalachew Genet
- Akalu Temesgen Yihunie
- Akinyemiju Tomi
- Akombi Blessing
- Al-Aly Ziyad
- Al-Mekhlafi Hesham M.
- Al-Raddadi Rajaa M.
- Alam Samiah
- Alamene Genet Melak
- Alanzi Turki M.
- Alema Niguse Meles
- Ali Beriwan Abdulqadir
- Ali Muhammad
- Alijanzadeh Mehran
- Alinia Cyrus
- Alipour Vahid
- Alizade Hesam
- Aljunid Syed Mohamed
- Almasi Afshin
- Almasi-Hashiani Amir
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J.
- Amare Azmeraw T.
- Amegah Adeladza Kofi
- Amini Saeed
- Amiri Fatemeh
- Amit Arianna Maever Loreche
- Anber Nahla Hamed
- Andrei Catalina Liliana
- Ansari Fereshteh
- Ansari-Moghaddam Alireza
- Anteneh Zelalem Alamrew
- Antonio Carl Abelardo T.
- Antriyandarti Ernoiz
- Anvari Davood
- Anwer Razique
- Appiah Seth Christopher Yaw
- Arab-Zozani Morteza
- Arabloo Jalal
- Araya Ephrem Mebrahtu
- Arefi Zohreh
- Aremu Olatunde
- Arnedo Carlos Alberto Marrugo
- Arzani Afsaneh
- Asadi-Aliabadi Mehran
- Asadi-Pooya Ali A.
- Asante Kwaku Oppong
- Asgari Samaneh
- Asghari Babak
- Ashagre Alebachew Fasil
- Asrat Anemaw A.
- Ataeinia Bahar
- Atalay Hagos Tasew
- Atnafu Desta Debalkie
- Atout Maha Moh’d Wahbi
- Ausloos Marcel
- Avokpaho Euripide F. G. A.
- Awasthi Ashish
- Ayanore Martin Amogre
- Aynalem Yared A. Asmare
- Azadmehr Abbas
- Azari Samad
- Azarian Ghasem
- Azene Zelalem Nigussie
- Babaee Ebrahim
- Badawi Alaa
- Badiye Ashish D.
- Bahrami Mohamad Amin
- Baig Atif Amin A.
- Bakhtiari Ahad
- Bakkannavar Shankar M.
- Balakrishnan Senthilkumar
- Balalami Nader Jafari
- Bali Ayele Geleto
- Banach Maciej
- Banik Palash Chandra
- Baradaran-Seyed Zahra
- Baraki Adhanom Gebreegziabher
- Barboza Miguel A.
- Barua Lingkan
- Basaleem Huda
- Basu Sanjay
- Bayati Mohsen
- Bayih Mulat Tirfie
- Baynes Habtamu Wondifraw
- Bedi Neeraj
- Behzadifar Masoud
- Behzadifar Meysam
- Bekele Yibeltal Alemu
- Bennett Derrick A.
- Berbada Dessalegn Ajema
- Berhe Abadi Kidanemariam
- Berhe Kidanemaryam
- Berman Adam E.
- Bernstein Robert S.
- Bhageerathy Reshmi
- Bhandari Dinesh
- Bharadwaj Pankaj
- Bhattacharjee Natalia V.
- Bhattacharyya Krittika
- Bijani Ali
- Bikbov Boris
- Bilano Ver
- Bililign Nigus
- Birara Setognal
- Birhane Minuye Biniam Biniam
- Birhanu Minyichil
- Biswas Raaj Kishore
- Bitew Zebenay Workneh
- Bogale Kassawmar Angaw
- Bohlouli Somayeh
- Bolla Srinivasa Rao
- Boloor Archith
- Borzouei Shiva
- Borzì Antonio M.
- Brady Oliver J.
- Bragazzi Nicola Luigi
- Braithwaite Dejana
- Briko Nikolay Ivanovich
- Britton Gabrielle
- Budhathoki Shyam S.
- Busse Reinhard
- Butt Zahid A.
- Bärnighausen Till Winfried
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- Massenburg Benjamin Ballard
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- Omer Muktar Omer
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- Shalash Ali S.
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- Shehata Hatem Samir
- Sheikhtaheri Abbas
- Shibuya Kenji
- Shiferaw Wondimeneh Shibabaw
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- Srivastava Rajni Kant Kant
- Starodubova Antonina
- Sudaryanto Agus
- Sufiyan Mu’awiyyah Babale
- Suleria Hafiz Ansar Rasul
- Sulo Gerhard
- Sunguya Bruno F.
- Syed Zahiruddin Quazi
- Sykes Bryan L.
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- Tabuchi Takahiro
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- Teklehaimanot Berhane Fseha
- Tekulu Gebretsadkan Hintsa
- Temsah Mohamad-Hani
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- Tessema Zemenu Tadesse
- Thomas Nihal
- Titova Mariya Vladimirovna
- Tlaye Kenean Getaneh
- Tohidinik Hamid Reza
- Tonelli Marcello
- Toroudi Hamidreza Pazoki
- Tovani-Palone Marcos Roberto
- Traini Eugenio
- Tran Khanh Bao
- Tripathi Manjari
- Uddin Riaz
- Ullah Irfan
- Unnikrishnan Bhaskaran
- Upadhyay Era
- Useh Ushotanefe
- Usman Muhammad Shariq
- Uthman Olalekan A.
- Vacante Marco
- Vaezghasemi Masoud
- Valdez Pascual R.
- VanderHeide John
- Varavikova Elena
- Varughese Santosh
- Vasankari Tommi Juhani
- Vasseghian Yasser
- Vecchia Carlo La
- Veisani Yousef
- Venkatesh Srinivasaraghavan
- Venketasubramanian Narayanaswamy
- Verma Madhur
- Vidale Simone
- Violante Francesco S.
- Vlassov Vasily
- Vollmer Sebastian
- Vukovic Rade
- Waheed Yasir
- Wang Haidong
- Wang Yafeng
- Wang Yuan-Pang
- Weldesamuel Girmay Teklay
- Werdecker Andrea
- Wiangkham Taweewat
- Wiens Kirsten E.
- Wijeratne Tissa
- Wolde Haileab Fekadu
- Wondafrash Dawit Zewdu
- Wonde Tewodros Eshete
- Wondmieneh Adam Belay
- Wu Ai-Min
- Xu Gelin
- Yadegar Abbas
- Yadollahpour Ali
- Yamada Tomohide
- Yano Yuichiro
- Yaya Sanni
- Yazdi-Feyzabadi Vahid
- Yeshaneh Alex
- Yeshaw Yigizie
- Yeshitila Yordanos Gizachew
- Yilma Mekdes Tigistu
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- Youm Yoosik
- Younis Mustafa Z.
- Yousefi Zabihollah
- Yousof Hebat-Allah Salah A.
- Yu Chuanhua
- Yusefzadeh Hasan
- Zahabi Saleh Salehi
- Zaki Leila
- Zaman Sojib Bin
- Zamani Mohammad
- Zamanian Maryam
- Zandian Hamed
- Zarafshan Hadi
- Zepro Nejimu Biza
- Zerfu Taddese Alemu
- Zewale Taye Abuhay
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Xiu-Ju
- Zodpey Sanjay
- Zomorodian Kamiar
- Zotor Francis Bruno
- Ärnlöv Johan
- Publication venue
- Nature Research
- Publication date
- 01/01/2020
- Field of study
Get PDFA double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic
The global burden of adolescent and young adult cancer in 2019 : a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbasi Behzad
- Abbasi-Kangevari Mohsen
- Abbasi-Kangevari Zeinab
- Abbastabar Hedayat
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdoli Amir
- Abebe Haimanot
- Abedi Aidin
- Abidi Hassan
- Abolhassani Hassan
- Abu-Gharbieh Eman
- Abubaker Ali Hiwa
- Achappa Basavaprabhu
- Acuna Juan Manuel
- Adedeji Isaac Akinkunmi
- Adegboye Oyelola A
- Adnani Qorinah Estiningtyas Sakilah
- Advani Shailesh M
- Afzal Muhammad Sohail
- Aghaie Meybodi Mohamad
- Ahadinezhad Bahman
- Ahinkorah Bright Opoku
- Ahmad Sajjad
- Ahmadi Sepideh
- Ahmed Rashid Tarik
- Ahmed Salih Yusra
- Ahmed Muktar Beshir
- Aiman Wajeeha
- Akalu Gizachew Taddesse
- Al Hamad Hanadi
- Al-Maweri Sadeq Ali
- Al-Raddadi Rajaa M
- Alahdab Fares
- AlAmodi Abdulhadi A
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Alem Adugnaw Zeleke
- Alem Dejene Tsegaye
- Alemayehu Yosef
- Alhalaiqa Fadwa Naji
- Alhassan Robert Kaba
- Ali Saqib
- Alicandro Gianfranco
- Alipour Vahid
- Aljunid Syed Mohamed
- Alkhayyat Motasem
- Alluri Sunitha
- Almasri Nihad A
- Almustanyir Sami
- Alvarez Elysia M
- Alvis-Guzman Nelson
- Ameyaw Edward Kwabena
- Amini Saeed
- Amu Hubert
- Ancuceanu Robert
- Andrei Catalina Liliana
- Andrei Tudorel
- Ansari Fereshteh
- Ansari-Moghaddam Alireza
- Anvari Davood
- Anyasodor Anayochukwu Edward
- Arab-Zozani Morteza
- Arabloo Jalal
- Argaw Ayele Mamo
- Ariffin Hany
- Arshad Muhammad
- Arulappan Judie
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- Winkler Andrea Sylvia
- Wubishet Befikadu Legesse
- Xu Rixing
- Xu Suowen
- Yahyazadeh Jabbari Seyed Hossein
- Yang Lin
- Yaya Sanni
- Yazdi-Feyzabadi Vahid
- Yazie Taklo Simeneh
- Yehualashet Sisay Shewasinad
- Yeshaneh Alex
- Yeshaw Yigizie
- Yirdaw Birhanu Wubale
- Yonemoto Naohiro
- Younis Mustafa Z
- Yousefi Zabihollah
- Yu Chuanhua
- Yunusa Ismaeel
- Zadnik Vesna
- Zahir Mazyar
- Zahirian Moghadam Telma
- Zamani Mohammad
- Zamanian Maryam
- Zandian Hamed
- Zare Fariba
- Zastrozhin Mikhail Sergeevich
- Zastrozhina Anasthasia
- Zhang Jianrong
- Zhang Zhi-Jiang
- Ziapour Arash
- Zoladl Mohammad
- Šekerija Mario
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Get PDFBackground In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15-39 years to define adolescents and young adults. Findings There were 1.19 million (95% UI 1.11-1.28) incident cancer cases and 396 000 (370 000-425 000) deaths due to cancer among people aged 15-39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59.6 [54.5-65.7] per 100 000 person-years) and high-middle SDI countries (53.2 [48.8-57.9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14.2 [12.9-15.6] per 100 000 person-years) and middle SDI (13.6 [12.6-14.8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23.5 million (21.9-25.2) DALYs to the global burden of disease, of which 2.7% (1.9-3.6) came from YLDs and 97.3% (96.4-98.1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe
The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali Amirali
- Abbas Qamar
- Abbasi Behzad
- Abbasi-kangevari Mohsen
- Abbasi-kangevari Zeinab
- Abbastabar Hedayat
- Abd-elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed Abdelwahab
- Abdoli Gholamreza
- Abdulkadir Hanan Abdulkadir
- Abedi Aidin
- Abegaz Kedir Hussein
- Abidi Hassan
- Aboagye Richard Gyan
- Abolhassani Hassan
- Absalan Abdorrahim
- Abtew Yonas Derso
- Abu-gharbieh Eman
- Abubaker Ali Hiwa
- Achappa Basavaprabhu
- Acheson Alistair R
- Acuna Juan Manuel
- Addison Daniel
- Addo Isaac Yeboah
- Adegboye Oyelola A
- Adesina Miracle Ayomikun
- Adnan Mohammad
- Adnani Qorinah Estiningtyas Sakilah
- Advani Shailesh M
- Afrin Sumia
- Afzal Muhammad Sohail
- Aggarwal Manik
- Ahinkorah Bright Opoku
- Ahmad Araz Ramazan
- Ahmad Rizwan
- Ahmad Sajjad
- Ahmad Sohail
- Ahmadi Sepideh
- Ahmed Rashid Tarik
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Muktar Beshir
- Aiman Wajeeha
- Ajami Marjan
- Akalu Gizachew Taddesse
- Akbarzadeh-khiavi Mostafa
- Aklilu Addis
- Akonde Maxwell
- Akunna Chisom Joyqueenet
- Al Hamad Hanadi
- Al-hanawi Mohammed Khaled
- Al-maweri Sadeq Ali Ali
- Al-raddadi Rajaa M
- Al-rifai Rami H Hani
- Al-sabah Salman Khalifah
- Al-tammemi Ala'a B
- Alahdab Fares
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Alessy Saleh Ali
- Algammal Abdelazeem M
- Alhassan Robert Kaba
- Ali Beriwan Abdulqadir
- Ali Liaqat
- Ali Syed Shujait
- Alimohamadi Yousef
- Alipour Vahid
- Aljunid Syed Mohamed
- Alkhayyat Motasem
- Almustanyir Sami
- Alonso Nivaldo
- Alqalyoobi Shehabaldin
- Altawalah Haya
- Alvis-guzman Nelson
- Amare Firehiwot
- Ameyaw Edward Kwabena
- Aminian Dehkordi Javad Javad
- Amirzade-iranaq Mohammad Hosein
- Amu Hubert
- Amusa Ganiyu Adeniyi
- Ancuceanu Robert
- Anderson Jason A
- Animut Yaregal Animut
- Anoushiravani Amir
- Anoushirvani Ali Arash
- Ansari-moghaddam Alireza
- Ansha Mustafa Geleto
- Antony Benny
- Antwi Maxwell Hubert
- Anwar Sumadi Lukman
- Anwer Razique
- Anyasodor Anayochukwu Edward
- Arab-zozani Morteza
- Arabloo Jalal
- Aremu Olatunde
- Argaw Ayele Mamo
- Ariffin Hany
- Aripov Timur
- Arshad Muhammad
- Artaman Al
- Arulappan Judie
- Aruleba Raphael Taiwo
- Aryannejad Armin
- Asaad Malke
- Asemahagn Mulusew A
- Asemi Zatollah
- Asghari-jafarabadi Mohammad
- Ashraf Tahira
- Assadi Reza
- Athar Mohammad
- Athari Seyyed Shamsadin
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- Attia Sameh
- Aujayeb Avinash
- Ausloos Marcel
- Avila-burgos Leticia
- Awedew Atalel Fentahun
- Awoke Mamaru Ayenew
- Awoke Tewachew
- Ayala Quintanilla Beatriz Paulina
- Ayana Tegegn Mulatu
- Ayen Solomon Shitu
- Azadi Davood
- Azadnajafabad Sina
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- Babajani Amirhesam
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- Badiye Ashish D
- Baghcheghi Nayereh
- Bagheri Nader
- Bagherieh Sara
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- 01/01/2022
- Field of study
Get PDFBackground Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe
The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019
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- Publication date
- 01/01/2022
- Field of study
Get PDFBACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
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- Publication venue
- Publication date
- 01/01/2020
- Field of study
Get PDFA double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4 (62.3 (55.1�70.8) million) to 6.4 (58.3 (47.6�70.7) million), but is predicted to remain above the World Health Organization�s Global Nutrition Target of <5 in over half of LMICs by 2025. Prevalence of overweight increased from 5.2 (30 (22.8�38.5) million) in 2000 to 6.0 (55.5 (44.8�67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic. © 2020, The Author(s)
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
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Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
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